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Transposons, also called transposable elements, are mobile genetic elements that generally have only modest target site selectively and can thus insert themselves into many different DNA sites. In transposition, a specific enzyme, usually encoded by the transposon and called a transpose, acts on a specific DNA sequence at each end of the transposon (first disconnecting it from the flanking DNA) and the inserting it into a new target DNA site. There is no requirement for homology between the ends of the element and the insertion site.