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Transcription and Enhancers
Like bacteria, eukaryotes use
gene regulatory proteins (activates and
repressors) to regulate the expression of their
genes but in somewhat different way. The DNA
sites to witch the eukaryote gene activates
bound were originally termed enhancers, since
their presence “enhanced”, or increased, the
rate of transcription dramatically. It came as a
surprise when, in 1979, in was discovered that
those activator proteins could be bound
thousands of nucleotide pairs away from
promoter.
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