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Genetic
Engineering
The popular terms
genetic engineering and genetic modification
refer to a biotechnology that manipulates
genetic material. This includes altering the DNA
of an organism many copies of the protein the
foreign DNA specifies. In the 1980s, researchers
began to apply recombinant DNA technology to
multicellular organisms, producing transgenic
plants and animals. Researchers add foreign DNA
at the one-cell stage (a gamete or fertilized
ovum). The transgenic organism that develops
from the original altered cell carries the
genetic change in every cell.
Yet another biotechnology, called gene
targeting, adds precision to transgenic
technology. Gene targeting “knocks out” or
“knocks in” the gene of interest at a particular
chromosomal locus, where it trades places with
an existing gene.
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